Daclizumab API Manufacturers
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Looking for Daclizumab API 152923-56-3?
- Description:
- Here you will find a list of producers, manufacturers and traders of Daclizumab. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Daclizumab
- Synonyms:
- Anti-IL-2 , Humanized antiCD25 , Ig gamma-1 chain C region
- Cas Number:
- 152923-56-3
- DrugBank number:
- DB00111
- Unique Ingredient Identifier:
- CUJ2MVI71Y
About Daclizumab
So, what does it do? Humanized IgG1 Mab that binds to the human interleukin-2 receptor (anti-Tac or anti-CD25). Daclizumab is a composite of human (90%) and murine (10%) antibody sequences. The human sequences were derived from the constant domains of human IgG1 and the variable framework regions of the Eu myeloma antibody. The murine sequences were derived from the complementarity-determining regions of a murine anti-Tac antibody.
On 22 April 2008, Roche Registration Limited chose to voluntarily withdraw the marketing authorization for their product Zenapax (daclizumab), as indicated for the prophylaxis of acute organ rejection in de novo allogeneic renal transplantation and used concomitantly with an immunosuppressive regimen like cyclosporine and corticosteroids in patients who are not hight immunized, for commercial reasons and confirmed that this decision was not related to any safety concerns associated with the use of Zenapax (daclizumab).
Check who is selling Daclizumab in the overview above.
