Venetoclax API Manufacturers
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Producer
Expertise in Low Volume, High Value (LVHV) APIs
Technical knowledge for high-tech API production
therapeutic production sites with GMP compliance
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Producer
All APIs are produced in Spain
Deep knowledge of international regulation
Niche, small-molecule API’s
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Producer
ISO9001 certified
Drug R&D center (in Hangzhou)
From lab scale (mg/g) to commercial scale (kgs/tons)
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Distributor
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Producer
Diverse portfolio of 180+APIs
1754+ DMF across global markets
1100+ patents filed, and more than 70 own patents granted
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Looking for Venetoclax API 1257044-40-8?
- Description:
- Here you will find a list of producers, manufacturers and traders of Venetoclax. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Venetoclax
- Synonyms:
- Cas Number:
- 1257044-40-8
- DrugBank number:
- DB11581
- Unique Ingredient Identifier:
- N54AIC43PW
About Venetoclax
Why are people looking for Venetoclax? Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process 1,. Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types of small lymphocytic lymphoma. CLL is the most prevalent leukemia diagnosed in Western countries.
Venetoclax was developed through reverse engineering of the BCL-2 protein family inhibitor, navitoclax. Venetoclax is approximately 10 times more potent than navitoclax with regard to induction of apoptosis in CLL cells. A new indication was approved in 2018 for the treatment patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), with or without 17p deletion, who have received at least one prior therapy. Previously, this drug was indicated only for patients with 17p gene deletion.
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Venetoclax is a type of Oncolytics
Oncolytics, as a subcategory of pharmaceutical active pharmaceutical ingredients (APIs), refers to compounds specifically designed to combat cancer cells. These powerful substances play a crucial role in the development of targeted cancer therapies. Oncolytic APIs are engineered to selectively target and destroy cancer cells while sparing healthy cells, minimizing potential side effects.
The efficacy of oncolytic APIs lies in their ability to disrupt cancer cell growth and induce cell death through various mechanisms. These APIs can directly target specific molecular pathways or receptors that are overexpressed or mutated in cancer cells, inhibiting their growth and proliferation. Additionally, oncolytic APIs can stimulate the immune system to recognize and eliminate cancer cells, harnessing the body's natural defenses against cancer.
The development of oncolytic APIs involves rigorous research and testing to ensure safety and efficacy. Pharmaceutical companies employ advanced technologies and methods to synthesize and optimize these compounds. They undergo preclinical and clinical trials to evaluate their therapeutic potential, dosing, and side effects.
Oncolytic APIs offer great promise in the field of cancer treatment, providing novel therapeutic options for patients. By precisely targeting cancer cells, they have the potential to enhance treatment outcomes and improve patient survival rates. Ongoing research and development in oncolytics continue to expand our understanding of cancer biology and revolutionize cancer treatment strategies.
Venetoclax (Oncolytics), classified under Anticancer drugs
Anticancer drugs belong to the pharmaceutical API (Active Pharmaceutical Ingredient) category designed specifically to combat cancer cells. These powerful medications play a crucial role in cancer treatment and are developed to target and destroy cancerous cells, preventing their growth and spread.
Anticancer drugs are classified based on their mode of action and can include various types such as chemotherapy drugs, targeted therapy drugs, immunotherapy drugs, and hormonal therapy drugs. Chemotherapy drugs work by interfering with the cell division process, thereby inhibiting the growth of cancer cells. Targeted therapy drugs, on the other hand, are designed to attack specific molecules or genes involved in cancer growth, minimizing damage to healthy cells. Immunotherapy drugs stimulate the body's immune system to recognize and destroy cancer cells. Hormonal therapy drugs are used in cancers that are hormone-dependent, such as breast or prostate cancer, to block the hormones that fuel cancer cell growth.
These APIs are typically synthesized through complex chemical processes in state-of-the-art manufacturing facilities. Stringent quality control measures ensure the purity, potency, and safety of these drugs. Anticancer APIs undergo rigorous testing and adhere to stringent regulatory guidelines before being approved for clinical use.
Due to their critical role in cancer treatment, anticancer drugs are in high demand worldwide. Researchers and pharmaceutical companies continually strive to develop new and more effective APIs in this category to enhance treatment outcomes and minimize side effects. The ongoing advancements in the field of anticancer drug development offer hope for improved cancer therapies and better patient outcomes.
Venetoclax manufacturers | traders | suppliers
We have 5 companies offering Venetoclax produced in 4 different countries.
Get in contact with the supplier of your choice:
- Tofigh Daru from Iran, product country of origin Iran
- LEBSA from Spain, product country of origin Spain
- Senova Technology Co., Ltd. from China, product country of origin China
- Shandong Octagon Chemicals Limited from China, product country of origin China
- Dr. Reddy's from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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