Sofosbuvir API Manufacturers
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Produced in:
Established in: 1987
MOQ: -
Passed ISO9001:2015 and SGS audit
Provide one-stop CDMO service from R&D to production
Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification
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Produced in:
Established in: 2011
MOQ: 1 kg
Employees: 10+
Fast Response and Good Communication
Willingness To Start From Small
Flexible Payment Terms
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Produced in:
Established in: 1944
MOQ: -
Employees: 4,000
14 international API plant sites
Portfolio of 350+ APIs
Teva is among the world’s largest generic drug/API manufacturers
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Looking for Sofosbuvir API 1190307-88-0?
- Description:
- Here you will find a list of producers, manufacturers and traders of Sofosbuvir. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
- API | Excipient name:
- Sofosbuvir
- Synonyms:
- Cas Number:
- 1190307-88-0
- DrugBank number:
- DB08934
- Unique Ingredient Identifier:
- WJ6CA3ZU8B
About Sofosbuvir
Why are people looking for Sofosbuvir? Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients Treatment options for chronic Hepatitis C have advanced significantly since 20 with the development of Direct Acting Antivirals (DAAs) such as sofosbuvir. As a prodrug nucleotide analog, Sofosbuvir is metabolized into its active form as the antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective substrate for NS5B (non-structural protein 5B) Synthesis. NS5B, an RNA-dependent RNA polymerase, is essential for the transcription of Hepatitis C viral RNA and for its high replicative rate and genetic diversity Sofosbuvir and other direct acting antivirals are therefore very potent options for the treatment of Hepatitis C, as they exhibit a high barrier to the development of resistance This is an important advantage relative to HCV drugs that target other viral enzymes such as the protease, for which rapid development of resistance has proven to be an important cause of therapeutic failure.
In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) recommend Sofosbuvir as first line therapy in combination with other antivirals for all six genotypes of Hepatitis C
Do you want to buy this product? Send an inquiry to the listed suppliers that meets your quality requirements.
Sofosbuvir is a type of Anti-HCV agents
Anti-HCV agents, belonging to the pharmaceutical API category, are potent medications used in the treatment of Hepatitis C Virus (HCV) infection. Hepatitis C is a viral disease that affects the liver and can lead to severe health complications if left untreated. Anti-HCV agents work by targeting specific mechanisms involved in the replication and spread of the HCV virus within the body.
These pharmaceutical APIs are designed to inhibit various steps of the viral lifecycle, including viral entry into liver cells, viral RNA replication, and assembly of new viral particles. By disrupting these critical processes, anti-HCV agents effectively reduce the viral load in the body, slow down disease progression, and ultimately improve patient outcomes.
The development of anti-HCV agents has revolutionized the management of HCV infection, offering new hope for patients. These APIs are often used in combination with other antiviral drugs to form highly effective treatment regimens known as direct-acting antiviral (DAA) therapies. DAAs have significantly higher cure rates compared to older treatment options, such as interferon-based therapies, and are associated with fewer side effects.
The pharmaceutical industry has made significant advancements in the development of anti-HCV agents, resulting in a diverse range of APIs with varying mechanisms of action. This diversity allows healthcare professionals to tailor treatment plans based on the specific characteristics of each patient's HCV infection, maximizing the chances of successful viral eradication.
In summary, anti-HCV agents are a crucial category of pharmaceutical APIs used in the treatment of Hepatitis C. Their targeted action against the HCV virus has revolutionized the management of this chronic infection, providing more effective and better-tolerated treatment options for patients.
Sofosbuvir manufacturers | traders | suppliers
We have 17 companies offering Sofosbuvir produced in 3 different countries.
Get in contact with the supplier of your choice:
- Sinoway industrial Co.,Ltd from China, product country of origin China
- Shandong Octagon Chemicals Limited from China, product country of origin China
- Laurus Labs from India, product country of origin India
- Shanghai Acebright from China, product country of origin China
- Honour Lab from India, product country of origin India
- Lupin from India, product country of origin India
- Hangzhou Coben Pharmaceutical Co Ltd from China, product country of origin China
- Teva API from Israel, product country of origin Unknown
- Kaiyuan Hengtai Pharma Co Ltd from China, product country of origin China
- Dalian Wista Pharma Co Ltd from China, product country of origin China
- Zhejiang Hongyuan from China, product country of origin China
- Beijing Huikang Boyuan from China, product country of origin China
- Changzhou Pharma from China, product country of origin China
- Hetero Labs from India, product country of origin India
- Mylan from India, product country of origin India
- MSN Life Sciences from India, product country of origin India
- Shaoxing Hantai Pharma from China, product country of origin China
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.
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