Dapagliflozin API Manufacturers

compare suppliers & get competitive offers

Filters

Reset

Selected filters:

Type
Production region
Qualifications
Country of origin

TOP RANKING

Located in:

China

Passed ISO9001:2015 and SGS audit

Provide one-stop CDMO service from R&D to production

Certifications: ISO9001: 2015, HALAL Certificate, Kosher Certification

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • GMP

  • CoA

  • ISO9001

  • MSDS

Contact supplier

Replies quickly

TOP RANKING

Located in:

Poland

Producer

Produced in:

Poland

Established in: 1951

MOQ: -

Employees: 455+

Largest Polish manufacturer of pharmaceuticals and a leader of the Polish pharmaceutical market.

FDA approved european manufcaturing facilities

Export APIs to more than 60 countries worldwide

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • FDA

  • DMF

  • GMP

  • CoA

  • EDMF/ASMF

  • MSDS

  • BSE/TSE

Contact supplier

Replies quickly

TOP RANKING

Located in:

Iran

Producer

Produced in:

Iran

Established in: 1956

MOQ: 1 kg

Employees: 200+

Expertise in Low Volume, High Value (LVHV) APIs

Technical knowledge for high-tech API production

therapeutic production sites with GMP compliance

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

  • GMP

Contact supplier

Replies quickly

TOP RANKING

Located in:

India

Producer

Produced in:

India

Established in: 1984

MOQ: -

Employees: 21,650

Diverse portfolio of 180+APIs

1754+ DMF across global markets

1100+ patents filed, and more than 70 own patents granted

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • WC

  • KDMF

  • GMP

  • CoA

  • EDMF/ASMF

  • FDA

  • MSDS

  • BSE/TSE

Contact supplier

Replies quickly

HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2014

MOQ: -

Employees: 1000+

10+ GMP compliant production lines with patented technologies

Export oriented with a presence in more than 70 countries

Most comprehensive local anesthetic supplier in China

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • ISO9001

Contact supplier

Replies quickly

HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2013

MOQ: 1 g

Employees: 25+

ISO9001 certified

Drug R&D center (in Hangzhou)

From lab scale (mg/g) to commercial scale (kgs/tons)

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

Contact supplier

Replies quickly

HIGHLIGHTED

Located in:

India
  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • MSDS

  • BSE/TSE

  • DMF

  • WHO-GMP

  • ISO9001

  • GMP

Contact supplier

Replies quickly

Produced in:

India

Established in: 1984

MOQ: -

Employees: 2000+

Vertically integrated company

Largest producer of Montelukast in the world

USFDA & WHO GMP approved API plants

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • WC

  • GMP

  • CoA

  • EDMF/ASMF

  • FDA

  • ISO9001

  • MSDS

  • BSE/TSE

Contact supplier

Replies quickly

Produced in:

China

Established in: 2019

MOQ: 1 kg

Employees: 10+

Focused on pharmaceutical industry

Reasonable price for the customers

Full service from R&D stage to commercial stage

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • BSE/TSE

  • DMF

  • MSDS

  • GMP

Contact supplier

Replies quickly

Produced in:

China

Established in: 2011

MOQ: 10 g

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • BSE/TSE

  • MSDS

Contact supplier

Replies in a day or 2

Producer

Produced in:

India

Established in: 1995

MOQ: -

Employees: 10000

Fermentation technology Experts

Partnerships with 1200 pharma companies in 100+ countries

US FDA, EMA, COFEPRIES, ANVISA, PMDA accreditations

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Contact supplier

Replies quickly

Located in:

India

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Contact supplier

Replies slower than most

Produced in:

India

Established in: 1983

MOQ: -

Employees: 200+

Presence in more than 75 countries in the world

We delivery top quality APIs as per global standards

manufacture 45+ APIs including 10 essential drugs

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Contact supplier

Replies slower than most

Located in:

India

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Contact supplier

Replies slower than most

Located in:

China
  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Contact supplier

Replies slower than most

Located in:

India

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Contact supplier

Replies slower than most

Located in:

France

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • CoA

Contact supplier

Replies slower than most

Located in:

Germany

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • CoA

Contact supplier

Replies slower than most

Located in:

India

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Contact supplier

Replies slower than most

Located in:

China
Contact supplier

Replies slower than most

Located in:

China

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Contact supplier

Replies slower than most

Located in:

China
Contact supplier

Replies slower than most

Located in:

India
  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • WC

  • CoA

  • DMF

Located in:

India

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • GMP

  • WC

  • CoA

  • DMF

Located in:

India

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Located in:

India
  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • coa

  • ISO

  • EDQM certificate 2017

  • FDA

Located in:

China

Located in:

India

Producer

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • DMF

  • CoA

Located in:

India

How does it work?

1
Register for free
icon

You can register for free as long as you are registering on behalf of a legal company related to the pharmaceutical industry

2
Start sourcing
icon

Search in the search bar the product that you’re looking for. We’ll show you an overview of all available suppliers. Use the filters to select the relevant suppliers only

3
Send inquiries
icon

Have you found interesting suppliers? Then it’s time to contact them. Use the send inquiry button and send them a message. You can send for each product, 3 inquiries per week

4
Get quotation
icon

Suppliers get notified by Pharmaoffer that they’ve received a new inquiry. They will come back to you with their questions, certificates, and offer in the chat on Pharmaoffer. We will send you an email in case of any news

5
Arrange agreement
icon

Does the supplier meet your quality and commercial requirements? Then you can place the order. Just follow the steps of our order module

Looking for Dapagliflozin API 461432-26-8?

Description:
Here you will find a list of producers, manufacturers and traders of Dapagliflozin. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Dapagliflozin 
Synonyms:
Dapagliflozin Amorphous , Dapagliflozin Propanediol  
Cas Number:
461432-26-8 
DrugBank number:
DB06292 
Unique Ingredient Identifier:
1ULL0QJ8UC

About Dapagliflozin

Here you will find more information about Dapagliflozin. Dapagliflozin is a sodium-glucose cotransporter 2 inhibitor indicated for managing diabetes mellitus type When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose resorption in the proximal tubule of the nephron and causing glycosuria1. Dapagliflozin was approved by the FDA on Jan 08, 20143.

More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.

Dapagliflozin is a type of SGLT2-inhibitors


SGLT2 inhibitors, short for Sodium-Glucose Co-Transporter 2 inhibitors, belong to the pharmaceutical API subcategory utilized in the treatment of type 2 diabetes mellitus (T2DM). These innovative drugs target the SGLT2 protein responsible for reabsorbing glucose in the kidneys, resulting in increased urinary glucose excretion.

By inhibiting SGLT2, these drugs effectively lower blood glucose levels and improve glycemic control in patients with T2DM. This mechanism of action is independent of insulin secretion or sensitivity, making SGLT2 inhibitors an attractive option for individuals who are resistant to or cannot tolerate other diabetes medications.

Some commonly prescribed SGLT2 inhibitors include canagliflozin, dapagliflozin, and empagliflozin. These pharmaceutical APIs are typically formulated into oral tablets, making them convenient for patient administration.

Clinical studies have demonstrated the effectiveness of SGLT2 inhibitors in reducing HbA1c levels, body weight, and blood pressure in patients with T2DM. Additionally, these medications have shown potential cardiovascular benefits, including a decreased risk of cardiovascular events.

However, it is important to note that SGLT2 inhibitors are not suitable for everyone, and their use should be carefully considered in patients with renal impairment or a history of ketoacidosis. Adverse effects may include genitourinary infections and increased risk of dehydration.

Overall, SGLT2 inhibitors are a promising class of pharmaceutical APIs that offer an innovative approach to managing T2DM by targeting renal glucose reabsorption. Ongoing research and development in this field aim to further optimize the therapeutic potential of SGLT2 inhibitors and improve patient outcomes.


Dapagliflozin (SGLT2-inhibitors), classified under Anti-diabetics


Anti-diabetics, belonging to the pharmaceutical API (Active Pharmaceutical Ingredient) category, are a group of compounds designed to manage and treat diabetes mellitus, a chronic metabolic disorder characterized by high blood sugar levels. These medications play a vital role in controlling diabetes and preventing complications associated with the disease.

Anti-diabetics encompass a wide range of drug classes, including biguanides, sulfonylureas, thiazolidinediones, dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT2) inhibitors, and glucagon-like peptide-1 (GLP-1) receptor agonists. Each class works through different mechanisms to regulate blood sugar levels and improve insulin sensitivity.

Biguanides, such as metformin, reduce glucose production by the liver and enhance insulin sensitivity in peripheral tissues. Sulfonylureas, like glipizide, stimulate insulin secretion from pancreatic beta cells. Thiazolidinediones, including pioglitazone, improve insulin sensitivity in muscle and adipose tissues. DPP-4 inhibitors, such as sitagliptin, increase insulin release and inhibit glucagon secretion. SGLT2 inhibitors, like dapagliflozin, decrease renal glucose reabsorption, leading to increased urinary glucose excretion. GLP-1 receptor agonists, such as exenatide, enhance insulin secretion, suppress glucagon release, slow gastric emptying, and promote satiety.

These anti-diabetic APIs serve as the foundational ingredients for the formulation of various oral tablets, capsules, and injectable medications used in the treatment of diabetes. By targeting different aspects of glucose regulation, they help patients achieve and maintain optimal blood sugar levels, thus reducing the risk of diabetic complications, such as cardiovascular disease, neuropathy, and nephropathy.

It is crucial for healthcare professionals to prescribe and administer these anti-diabetic medications appropriately, considering factors like the patient's medical history, co-existing conditions, and potential drug interactions. Regular monitoring of blood glucose levels and close medical supervision are necessary to ensure effective diabetes management.

In conclusion, anti-diabetics form a critical category of pharmaceutical APIs used for the treatment of diabetes. These compounds, encompassing various drug classes, work through distinct mechanisms to regulate blood sugar levels and improve insulin sensitivity. By facilitating glucose control, anti-diabetic APIs help mitigate the risk of complications associated with diabetes mellitus, ultimately promoting better health outcomes for patients.



Dapagliflozin manufacturers | traders | suppliers

We have 29 companies offering Dapagliflozin produced in 6 different countries.

Get in contact with the supplier of your choice:

  • Sinoway industrial Co.,Ltd from China, product country of origin China
  • Polpharma from Poland, product country of origin Poland
  • Tofigh Daru from Iran, product country of origin Iran
  • Dr. Reddy's from India, product country of origin India
  • Shandong Chenghui Shuangda Pharmaceutical Co. Ltd. from China, product country of origin China
  • Senova Technology Co., Ltd. from China, product country of origin China
  • Solfyn International LLP from India, product country of origin China
  • Morepen Laboratories Ltd. from India, product country of origin India
  • Apino Pharma Co., Ltd. from China, product country of origin China
  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • Biocon from India, product country of origin India
  • Raks Pharma from India, product country of origin India
  • Harman Finochem from India, product country of origin India
  • Honour Lab from India, product country of origin India
  • Jiangsu Hansoh Pharma from China, product country of origin China
  • Hikal from India, product country of origin India
  • Finorga from France, product country of origin France
  • Siegfried from Germany, product country of origin Germany
  • Lupin from India, product country of origin India
  • Fuxing Long Rui Pharma from China, product country of origin China
  • ALP PHARM from China, product country of origin China
  • Jiangxi Aifeimu Technology Co Ltd from China, product country of origin China
  • Glenmark Pharma from India, product country of origin India
  • MSN Labs. from India, product country of origin India
  • Sun Pharma from India, product country of origin India
  • ZCL Chemicals from India, product country of origin India
  • Shaoxing Hantai Pharma from China, product country of origin China
  • Micro Labs from India, product country of origin India
  • Piramal Pharma Solutions from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

You can use the filters to find high-quality suppliers. For example, you can select GMP, FDA or ISO certified suppliers. Visit our FAQ page or use the chat box in the corner to get more information about Pharmaoffer.