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Daclatasvir | compare suppliers & send inquiries for free

Here you will find a list of producers, manufacturers and traders of Daclatasvir. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
Apino Pharma Co., Ltd.

MOQ: 1 kg
Type: Producer
Origin: China
China
Optimus Drugs Pvt Ltd

MOQ: 10 kg
Type: Producer
Origin: India
India
Mylan


Type: Producer
Origin: India
India
Shaoxing Hantai Pharma


Type: Trader
Origin: China
China
Glenmark Pharma


Type: Producer
Origin: India
India
Hetero Labs


Type: Producer
Origin: India
India
Laurus Labs


Type: Producer
Origin: India
India
MSN Life Sciences


Type: Producer
Origin: India
India
Fuxing Long Rui Pharma


Type: Producer
Origin: China
China
Cipla


Type: Producer
Origin: India
India
Beijing Mesochem Technology Co Ltd


Type: Producer
Origin: China
China

Looking for Daclatasvir 1009119-64-5?

API | Excipient name:
Daclatasvir 
Synonyms:
 
Cas Number:
1009119-64-5 
DrugBank number:
DB09102 
Unique Ingredient Identifier:
LI2427F9CI

About Daclatasvir

Want to know what Daclatasvir is used for? Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. It is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt form . Hepatitis C is an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients Daclatasvir was the first drug with demonstrated safety and therapeutic efficacy in treating HCV genotype 3 without the need for co-administration of interferon or Ribavirin.

It exerts its antiviral action by preventing RNA replication and virion assembly via binding to NS5A, a nonstructural phosphoprotein encoded by HCV. Binding to the N-terminus of the D1 domain of NS5A prevents its interaction with host cell proteins and membranes required for virion replication complex assembly. Daclatasvir is shown to target both the cis- and trans-acting functions of NS5A and disrupts the function of new HCV replication complexes by modulating the NS5A phosphorylation status The most common critical NS5A amino acid substitutions that led to reduced susceptibility to daclatasvir therapy occured at position Q30 (Q30H/K/R) and M28 in genotype 1a patients and Y93H in genotype 3 patients. According to 2017 American Association for the Study of Liver Diseases (AASLD), 60mg of daclatasvir is recommended with 400mg.

Ask the supplier for a certificate of analysis to find out more about the quality of Daclatasvir.

Daclatasvir manufacturers | traders | suppliers
We have 11 companies offering Daclatasvir from 2 different countries.

Get in contact with the supplier of your choice:

  • Apino Pharma Co., Ltd. from China
  • Optimus Drugs Pvt Ltd from India
  • Mylan from India
  • Shaoxing Hantai Pharma from China
  • Glenmark Pharma from India
  • Hetero Labs from India
  • Laurus Labs from India
  • MSN Life Sciences from India
  • Fuxing Long Rui Pharma from China
  • Cipla from India
  • Beijing Mesochem Technology Co Ltd from China

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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