Cyclosporine API Manufacturers

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HIGHLIGHTED

Located in:

Germany

Produced in:

Italy

Established in: 1886

MOQ: 100 g

Employees: 275+

Raw materials, CMO and OTC products

Two GMP certified locations

Customisable (small-sized) packages

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

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  • MSDS

  • BSE/TSE

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HIGHLIGHTED

Located in:

China

Produced in:

China

Established in: 2011

MOQ: 100 g

Employees: 10+

Fast Response and Good Communication

Willingness To Start From Small

Flexible Payment Terms

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  • FDA

  • DMF

  • + 0

All certificates

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Produced in:

Unknown

Established in: 1963

MOQ: -

Employees: 800+

World’s 1st exclusive API distributor

Portfolio of 600+ APIs

>250 clients in Europe

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  • DMF

  • + 0

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Produced in:

China

Established in: 2019

MOQ: 1 kg

Employees: 10+

Focused on pharmaceutical industry

Reasonable price for the customers

Full service from R&D stage to commercial stage

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • CoA

  • BSE/TSE

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Produced in:

China

Established in: 1923

MOQ: 25 kg

Employees: 20+

Service-oriented company

Global supply chain resilience

Support of your new projects from start to commercial realisation

  • CoA

  • GMP

  • CEP

  • FDA

  • DMF

  • + 0

All certificates

  • WC

  • GMP

  • CoA

  • MSDS

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Located in:

China
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  • WC

  • CoA

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Replies slower than most

Located in:

China
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  • coa

  • JDMF

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Replies slower than most

Located in:

Germany

Distributor

  • CoA

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  • coa

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Replies slower than most

Producer

Produced in:

Unknown

Established in: 1944

MOQ: -

Employees: 4,000

14 international API plant sites

Portfolio of 350+ APIs

Teva is among the world’s largest generic drug/API manufacturers

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  • CEP

  • FDA

  • DMF

  • + 0

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  • DMF

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Located in:

South Korea

Producer

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  • DMF

  • + 0

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  • DMF

  • coa

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Located in:

France

Distributor

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Replies slower than most

Located in:

Italy

Producer

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Located in:

China
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Replies slower than most

Located in:

United States

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Located in:

Italy

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  • DMF

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  • coa

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Looking for Cyclosporine API 59865-13-3?

Description:
Here you will find a list of producers, manufacturers and traders of Cyclosporine. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Cyclosporine 
Synonyms:
Ciclosporin , CsA , CyA , Cyclosporin A , Ciclosporin  
Cas Number:
59865-13-3 
DrugBank number:
DB00091 
Unique Ingredient Identifier:
83HN0GTJ6D

About Cyclosporine

Here is a short description about Cyclosporine. Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).

You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet and DMF.

Cyclosporine is a type of Immunosuppressants


Immunosuppressants are a vital subcategory of pharmaceutical active pharmaceutical ingredients (APIs) that play a crucial role in medical treatments. These substances are designed to suppress or weaken the immune system's response, making them invaluable in various therapeutic applications.

Immunosuppressants find extensive use in the management of autoimmune diseases, organ transplantation, and the prevention of rejection reactions. By modulating the immune system's activity, these APIs help control excessive immune responses that can lead to tissue damage and chronic inflammation.

There are different classes of immunosuppressants, including corticosteroids, calcineurin inhibitors, antimetabolites, and biologics. Each class targets specific immune pathways to achieve the desired therapeutic effect. Corticosteroids, for instance, are known for their potent anti-inflammatory properties, making them effective in managing conditions such as rheumatoid arthritis and asthma.

Calcineurin inhibitors like cyclosporine and tacrolimus act by inhibiting the activity of calcineurin, a protein involved in immune cell activation. These drugs are commonly used in organ transplantation to prevent the immune system from attacking the transplanted organ.

Antimetabolites interfere with DNA synthesis and cell proliferation, thereby dampening immune responses. They are often prescribed for conditions like psoriasis and rheumatoid arthritis.

Biologic immunosuppressants, such as monoclonal antibodies, target specific immune cells or molecules involved in the disease process. They have revolutionized the treatment of autoimmune diseases like rheumatoid arthritis, Crohn's disease, and psoriasis.

Immunosuppressants require careful administration and monitoring due to their potential side effects and interactions with other medications. Close collaboration between healthcare professionals, pharmacists, and patients is essential to ensure the safe and effective use of these APIs in various therapeutic settings.

Overall, immunosuppressants represent a critical category of pharmaceutical APIs that significantly contribute to improving patients' quality of life by controlling the immune system's activity and managing various autoimmune conditions and transplantation outcomes.


Cyclosporine (Immunosuppressants), classified under Immunomodulators


Immunomodulators, a category of pharmaceutical active pharmaceutical ingredients (APIs), are substances that help regulate and modify the immune response of an individual. These compounds play a crucial role in treating various immune-related disorders and diseases. Immunomodulators work by either enhancing or suppressing the immune system, depending on the specific condition being treated.

Immunomodulators are used in the treatment of autoimmune disorders, such as rheumatoid arthritis, multiple sclerosis, and psoriasis. By suppressing the immune system, these APIs help reduce the overactive immune response associated with these conditions, thereby alleviating symptoms and preventing further damage to the body's tissues.

On the other hand, immunomodulators are also employed to boost the immune system in cases of immunodeficiency disorders. These APIs stimulate the immune response, enabling the body to better fight off infections and diseases. Additionally, immunomodulators are utilized in the prevention and treatment of organ transplant rejection, where they help modulate the immune system to accept the transplanted organ.

The development and production of immunomodulators require rigorous testing and quality control to ensure their safety and efficacy. Pharmaceutical companies carefully formulate these APIs into various dosage forms, including tablets, capsules, injections, and topical preparations, to cater to different patient needs.

In summary, immunomodulators form a vital category of pharmaceutical APIs that regulate and modify the immune system. With their ability to modulate immune responses, these compounds contribute significantly to the management and treatment of various immune-related disorders and diseases, improving the quality of life for many patients.



Cyclosporine manufacturers | traders | suppliers

We have 15 companies offering Cyclosporine produced in 5 different countries.

Get in contact with the supplier of your choice:

  • Caesar & Loretz GmbH (CAELO) from Germany, product country of origin Italy
  • Shandong Octagon Chemicals Limited from China, product country of origin China
  • TIEFENBACHER API + Ingredients from Germany, product country of origin Unknown
  • Apino Pharma Co., Ltd. from China, product country of origin China
  • Otto Brandes GmbH from Germany, product country of origin China
  • Fujian Kerui from China, product country of origin China
  • Hangzhou Zhongmei Huadong from China, product country of origin China
  • Flavine from Germany, product country of origin Unknown
  • Teva API from Israel, product country of origin Unknown
  • CKD Bio from South Korea, product country of origin South Korea
  • Socosur from France, product country of origin Unknown
  • Euticals from Italy, product country of origin Unknown
  • Ruibang Laboraties from China, product country of origin China
  • Abbvie from United States, product country of origin United States
  • Sicor from Italy, product country of origin Italy

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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