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Supply to over 40 countries around the globe

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Established in: 1923

MOQ: 25 kg

Employees: 20+

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Looking for Bosentan API 147536-97-8?

Description:
Here you will find a list of producers, manufacturers and traders of Bosentan. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation and more. Send inquiries for free and get in direct contact with the supplier of your choice.
API | Excipient name:
Bosentan 
Synonyms:
bosentán , bosentan , bosentanum  
Cas Number:
147536-97-8 
DrugBank number:
DB00559 
Unique Ingredient Identifier:
XUL93R30K2

About Bosentan

So, what does it do? Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.

You can find more info about this product by clicking on the DB ID above.

Bosentan is a type of Vasodilators


Vasodilators are a crucial subcategory of pharmaceutical Active Pharmaceutical Ingredients (APIs) that play a significant role in the management of various cardiovascular conditions. These medications work by widening the blood vessels, promoting increased blood flow and reducing peripheral resistance.

Vasodilators are commonly prescribed to treat hypertension (high blood pressure), angina (chest pain), and heart failure. They are designed to relax and dilate the smooth muscle cells in the walls of blood vessels, leading to improved circulation and reduced strain on the heart.

One widely used class of vasodilators is calcium channel blockers, which prevent calcium from entering the muscle cells of blood vessels. This action inhibits muscle contraction, resulting in widened arteries and enhanced blood flow. Another class is nitric oxide (NO) donors, which release NO, a potent vasodilator, to promote relaxation of vascular smooth muscles.

The therapeutic benefits of vasodilators extend beyond cardiovascular disorders. Some vasodilators, such as minoxidil, have been repurposed for treating male pattern baldness. These medications stimulate hair growth by dilating blood vessels around hair follicles, enhancing nutrient and oxygen delivery.

As with any pharmaceutical API, vasodilators must meet strict quality standards and regulatory guidelines to ensure safety and efficacy. Manufacturers employ sophisticated production processes and stringent quality control measures to guarantee the purity, potency, and stability of these APIs.

In conclusion, vasodilators are a vital subcategory of pharmaceutical APIs used to manage cardiovascular conditions. By expanding blood vessels and enhancing blood flow, vasodilators contribute to improved patient outcomes and play a critical role in the treatment of hypertension, angina, heart failure, and even hair loss.


Bosentan (Vasodilators), classified under Antihypertensive agents


Antihypertensive agents are a crucial category of pharmaceutical active pharmaceutical ingredients (APIs) used to treat high blood pressure, also known as hypertension. These medications are designed to lower blood pressure and reduce the risk of associated cardiovascular complications.

Antihypertensive agents function by targeting various mechanisms involved in blood pressure regulation. Some common classes of antihypertensive agents include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and diuretics.

ACE inhibitors work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a hormone that constricts blood vessels. ARBs, on the other hand, block the receptors to which angiotensin II binds, thereby preventing its vasoconstrictive effects.

Beta-blockers reduce blood pressure by blocking the effects of adrenaline and noradrenaline, which are responsible for increasing heart rate and constricting blood vessels. CCBs inhibit calcium from entering the smooth muscles of blood vessels, resulting in relaxation and vasodilation. Diuretics promote the elimination of excess fluid and sodium from the body, reducing blood volume and thereby lowering blood pressure.

Antihypertensive agents are typically prescribed based on the individual patient's condition and specific needs. They can be used alone or in combination to achieve optimal blood pressure control. It is important to note that antihypertensive agents should be taken regularly as prescribed by a healthcare professional and may require periodic monitoring to ensure their effectiveness and manage any potential side effects.

In summary, antihypertensive agents play a vital role in the management of hypertension by targeting various mechanisms involved in blood pressure regulation. These medications offer significant benefits in reducing the risk of cardiovascular complications associated with high blood pressure.



Bosentan manufacturers | traders | suppliers

We have 23 companies offering Bosentan produced in 6 different countries.

Get in contact with the supplier of your choice:

  • Hari Ganesh Pharma Private Limited from India, product country of origin India
  • AMARI TRADE ALLIANEC LLP from India, product country of origin India
  • Otto Brandes GmbH from Germany, product country of origin India
  • Honour Lab from India, product country of origin India
  • Huanggang Luban Pharmaceutical Co Ltd from China, product country of origin China
  • Shiratori Pharmaceutical from Japan, product country of origin Japan
  • Jeil Pharmaceutical from South Korea, product country of origin South Korea
  • Parabolic Drugs from India, product country of origin India
  • Dishman Pharmaceuticals and Chemicals from India, product country of origin India
  • Natco Pharma from India, product country of origin India
  • Raks Pharma from India, product country of origin India
  • Megafine Pharma (P) Ltd. from India, product country of origin India
  • Amino Chemicals from Malta, product country of origin Malta
  • Triquim from Argentina, product country of origin Argentina
  • Ehfield Co.,Ltd from China, product country of origin China
  • Jubilant Generics from India, product country of origin India
  • Glenmark Pharma from India, product country of origin India
  • Cipla from India, product country of origin India
  • Divis Labs. from India, product country of origin India
  • Sun Pharma from India, product country of origin India
  • Mylan from India, product country of origin India
  • MSN Labs. from India, product country of origin India
  • Malladi Drugs & Pharma from India, product country of origin India

Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum or a specific purity.

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