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You can find a short description about Adapalene here. Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris.
Adapalene has similar efficacy but a superior safety profile compared to tretinoin. Tazarotene is more efficacious than adapalene but is designated as pregnancy category X and hence is contraindicated in pregnant women. Adapalene can also be combined with benzoyl peroxide (BPO), which possesses bactericidal properties6, and either adapalene alone, or adapalene BPO combination products, are commonly used to treat mild-to-severe acne. Differin®, produced by Galderma Labs, was first granted FDA approval on May 31st, 1996, as a 0.1% adapalene topical solution. Differin was later made available as 0.1% gel, cream, or lotion, or 0.3% gel products. On December 8th, 2008, Galderma Labs gained FDA approval for Epiduo®, a 0.1% adapalene, 2.5% BPO combination gel.
More information such as the structure, indication or toxicity is available on Drugbank, click the ID above.
Adapalene manufacturers | traders | suppliers
We have 12 companies offering Adapalene from 4 different countries.
Get in contact with the supplier of your choice:
- Medica Pharma Chem from India
- Sun Pharma from India
- Olon from Italy
- Shaoxing Hantai Pharma from China
- Glenmark Pharma from India
- Aarti Industries from India
- Excella from Germany
- Medichem from Spain
- Teva from Israel
- Bal Pharma from India
- Taro Pharma from Israel
- Finorga from France
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